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ObjectiveTo explore the effect of emotional catharsis on the mental health status， coping style and satisfaction with the intervention among adolescents in Nanchong in the post-pandemic period. MethodsCompletely random sampling method was used to recruit 390 adolescents from 2 general secondary schools， 2 county secondary schools and 2 universities in Nanchong from January 2021 to April 2022. The subjects were divided into study group （n=195） and control group （n=195） by random number table method. The study group received emotional catharsis intervention. The control group received self-regulation and relaxation without any other intervention. Interventions for both groups lasted for 3 months. Before and after the intervention， the mental health status and coping style of the adolescents were assessed using the Symptom Checklist 90 （SCL-90） and the Simplified Coping Style Questionnaire （SCSQ）. Also， the participants rated the satisfaction with the intervention via self-made satisfaction questionnaire after the intervention. ResultsAfter intervention， the total SCL-90 score of study group was lower than that of control group （t=68.312， P<0.01）. In terms of SCSQ， study group scored higher on the positive coping dimension （t=30.488， P<0.01）， and lower on negative coping dimension （t=46.562， P<0.01） than those of control group. There were 190 （98.96%） cases satisfied with the intervention in the study group and 175 （89.74%） cases in the control group， the difference of intervention satisfaction rate between the two groups was statistically significant （χ²=15.321， P<0.01）. ConclusionIn the post-pandemic period， emotional catharsis may be conducive to improve the mental health status and coping style among adolescents in Nanchong， and adolescents have high levels of satisfaction with the intervention.
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Objective@#To explore the relationship between the muscle mass index (MMI) and the aggregation of cardiovascular risk factors (CVRFs) in children and adolescents, and to provide a scientific basis for the prevention and treatment of cardiovascular diseases in children and adolescents.@*Methods@#The current situation study design was adopted, and 1 622 children and adolescents aged 12-17 years old in Yinchuan City were selected by a cluster random sampling method. All subjects were subjected to questionnaire survey, physical examination, body composition determination and laboratory index testing.@*Results@#When other variables were not adjusted, MMI was a risk factor for the aggregation of cardiovascular risk factors ( P <0.01). After adjusting for age, gender and BMI, MMI became a protective factor for CVRFs≥1 ( OR =0.74, 95% CI =0.62-0.89), compared with insufficient MMI, the risk of developing CVRFs≥1 with good MMI and sufficient MMI was 0.60(95% CI =0.46-0.79), 0.56(95% CI =0.37- 0.85 ) times. The risk of CVRFs≥2 was 0.54(95% CI =0.37-0.79), 0.51(95% CI =0.30-0.87) times, and similar results were found in boys ( P <0.05). @*Conclusion@#Under the same BMI level, muscle mass index is a protective factor for cardiovascular risk factor aggregation in children and adolescents. Physical exercise of children and adolescents should be emphasized to maintain the best muscle mass and weight.
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ObjectiveTo analyze the current status and correlation of occupational commitment and job burnout in nurses. MethodsOccupational commitment scale and Maslach Burnout Inventory General Survey （MBI-GS） were used to survey 695 nurses in 4 hospitals in Nanchong， and the assessment results were compared among nurses with different demographic characteristics， thereafter， Pearson correlation analysis was conducted to discuss the correlation between occupational commitment and job burnout in nurses. ResultsThe total scores of occupational commitment scale and MBI-GS of nurses were （78.38±12.33） and （37.05±9.61）， respectively. The total occupational commitment scale score showed significant differences among nurses of different hospitals， departments， working years and genders （P<0.05 or 0.01）， and the total MBI-GS score showed statistical differences among nurses of different hospitals， departments， ages， professional titles， working years， educational level and marital status （P<0.05 or 0.01）. Pearson correlation analysis showed that the total score and each dimension score of MBI-GS were negatively correlated with the total score of occupational commitment scale， as well as the scores of affective commitment， normative commitment and economic cost commitment （r=-0.517~-0.075，P<0.05 or 0.01）. The emotional cost commitment score was negatively correlated with the the total MBI-GS score， along with the scores in professional efficacy and depersonalization dimensions （r=-0.172~-0.098， P<0.01）. The score of opportunity commitment was positively correlated with the score of professional efficacy （r=0.106， P<0.01）， and negatively correlated with the score of emotional exhaustion and depersonalization （r=-0.156， -0.123， P<0.01）. ConclusionThe hospital， department and working years of the nurses are the common factors influencing occupational commitment and job burnout. The occupational commitment is higher in female nurses than that in male nurses， and the job burnout is more severe in the unmarried than that in the married， moreover， the job burnout of the nurses is negatively correlated with occupational commitment.
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Objective:To observe the antibacterial effect of Ag +-loaded TiO 2 (Ag -TiO 2) and Ag -TiO 2 coated endotracheal tube (ETT) on the bacterial biofilm (BF) of Staphylococcus aureus. Methods:2, 3-bis-(2-methoxy- 4-nitro-5-sulfophenyl)-2H-tetrazolium-5-carboxanilide (XTT) colorimetric method was used to detect minimal inhibitory concertation (MIC) of Ag-TiO 2 for inhibition of BF of Staphylococcus aureus. The Ag -TiO 2 coated ETT were prepared, and divided into 11 mg/L, 8 mg/L, 5 mg/L, 2 mg/L and 0 mg/L ETT group, according to the concentration gradient, then impregnated in the liquid with Staphylococcus aureus at a concentration of 1.0×10 9cfu/L. The influence of antibacterial coated ETT on the formation of Staphylococcus aureus BF was determined by detecting the colonies of bacteria and BF on the ETT. Results:Ag-TiO 2 had a significant inhibitory effect on Staphylococcus aureus BF in a concentration -dependent manner, and its MIC was 10 mg/L. Ag -TiO 2 coated ETT has significant anti -Staphylococcus aureus BF effect, and the higher the concentration, the stronger the effect. The absorbance ( A) values of Ag -TiO 2 5 mg/L, 8 mg/L, 11 mg/L ETT groups were significantly lower than that in control group (0.176±0.004, 0.147±0.002, 0.094±0.002 vs. 0.267±0.045, all P < 0.05). The inhibitory rates of Ag -TiO 2 2 mg/L, 5 mg/L, 8 mg/L ETT groups were increased gradually, and 11 mg/L Ag -TiO 2 coated ETT group had the highest inhibitory rate for BF, the inhibitory rates were 6.4%, 34.1%, 44.9% and 64.8%, respectively. Conclusion:Both Ag-TiO 2 and Ag-TiO 2 coated ETT have significant inhibitory effects on Staphylococcus aureus BF.
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Objective To investigate the frequency of JAK2 V617F mutation and JAK2 V617F mutation allele burden in patients with essential thrombocythemia (ET), and explore the relationship between mutation and hematological parameters and coagulation function. Methods The clinical and laboratory parameters of 90 ET patients were analyzed. JAK2 V617F mutation was detected by AS-PCR and the mutation allele burden of JAK2 V617F was detected by qPCR. The correlation between mutation frequency and mutation burden of JAK2 V617F and blood laboratory parameters were investigated in ET. Results JAK2 V617F mutation was found in 50 patients (55.6 %). RBC [(4.67±0.89)×109/L vs (4.04±0.99)×109/L, P =0.003], WBC (11.64±5.20)×109/L vs (9.11±4.11)×109/L, P = 0.014], HCT (0.41±0.07) vs (0.36±0.07), P =0.005) in the JAK2 V617F mutated group were higher than those in the wild-type group. PT in mutated patients was longer than that in wild-type group [(13.18±1.63) s vs (12.02±1.24) s, P = 0.000]. The JAK2 V617F mutation allele burden was (29.91 ±18.63) %. No significant correlation was found between JAK2 V617F mutation allele burden and hematological parameters such as WBC, RBC and Plt (all P>0.05), but the JAK2 V617F mutation allele burden had a significant correlation with FDP (r = 0.456, P = 0.001). Conclusions JAK2 V617F mutation occurs in significant percentage patients with ET. Detection of JAK2 V617F mutation allele burden at diagnosis may play an important role in the early prevention of vascular events.